BOOSTING THE INNATE IMMUNE SYSTEM

Even with current vaccines, anti-virals and antibiotics significant unmet needs remain to better prevent and treat respiratory infections. Pulmotect technology has demonstrated activity and completed Phase I clinical trials to address these unmet needs.

PULMOTECT, INC. is a bio-pharmaceutical company that develops products (host-directed/pathogen-agnostic) to reduce morbidity and mortality in patients at risk of severe respiratory diseases.

IMMUNOCOMPROMISED PATIENTS

Forecast sales for the immuno-stimulants market are estimated to reach $17.6 billion.

The Cancer Market Outlook: Competitive landscape, pipeline analysis and growth opportunities

COPD EXACERBATIONS

COPD, which includes chronic bronchitis and emphysema, affects more than 24 million Americans and is the third leading cause of death in the U.S.

Centers for Disease Control

EPIDEMIC AND EMERGING PATHOGENS

More than 2 billion people worldwide could be impacted by a pandemic. Despite remarkable advances in medical research and treatments during the 20th century, infectious diseases remain among the leading causes of death worldwide.

National Institute of Allergy and Infectious Disease

Our Product

Pulmotect’s lead product, PUL-042, is a clinical stage inhaled therapeutic that in preclinical studies stimulates the innate immune system in minutes to provide immediate and effective protection that lasts for days against all major classes of pathogens.

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Our Research

Two previously completed phase I clinical trials demonstrated that PUL-042 was well tolerated in healthy individuals. A Phase IIa viral challenge study is ongoing and Phase II studies are being planned to assess the effectiveness of PUL-042 in preventing respiratory tract complications in immunocompromised cancer patients.

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The Market

Pulmotect’s initial focus is on the reduction of complications in cancer patients undergoing chemotherapy. Additional potential indications include reductions of COPD exacerbations, which are characterized by an acute worsening of symptoms, mostly precipitated by a bacterial or viral infection. Further unmet medical needs include treatment of viral infections, such as influenza.

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