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Our Approach

  • Overview
  • Published Journal Articles
  • Molecular Drivers of Synergy
    NAR Genomics and Bioinformatics; 2022, Vol. 4; No. 2
  • Modulation of the Pulmonary Innate Immune Response Does Not Change Lung Microbiota
    Am J Respir and Crit Care Med; Volume 204 Number 6, September 15 2021
  • Airway Epithelial Innate Immunity
    November 2021; Volume 12; Article 749077
  • PUL-042 Protection Against Coronavirus
    Am J Respir Cell Mol Biol 2020 Oct;63(4):540-541. doi: 10.1165/rcmb.2020-0247LE
  • Host‑directed therapy in foals can enhance functional innate immunity and reduce severity of Rhodococcus equi pneumonia
    Nature Scientific Reports 2021 11:2483 doi: 10.1038/s41598-021-82049-y
  • Combined aerosolized Toll-like receptor ligands are an effective therapeutic agent against influenza pneumonia when co-administered with oseltamivir
    Eur J Pharmacol.
  • Immune modulation to improve survival of respiratory virus infections in mice
    University of Texas MD Anderson Cancer Center UTHealth
  • Inducible epithelial resistance against acute Sendai virus infection prevents chronic asthma-like lung disease in mice
    Br J Pharmacol. 2020 Jan 22. doi: 10.1111/bph.14977.
  • Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections
    mbio.asm.org
  • Combined aerosolized Toll-like receptor ligands are an effective therapeutic agent against influenza pneumonia when co-administered with oseltamivir
    Eur J Pharmacol. 2018 January 05
  • Lung epithelial cells: therapeutically inducible effectors of antimicrobial defense
    Mucosal Immunol. 2017 Aug 16. doi: 10.1038/mi.2017.71. Review.
  • Inducible epithelial resistance protects mice against leukemia-associated pneumonia
    Blood. 2016 Aug 18. Volume 128(7): 982-92. doi: 10.1182/blood-2016-03-708511
  • Inducible epithelial resistance protects mice against leukemia-associated pneumonia – Commentary
  • Activation of lung toll-like receptors does not exacerbate sickness responses to lipopolysaccharide in mice Brain Behavior and Immunity
    2014 May. 38:211-9. doi: 10.1016/j.bbi.2014.02.004.
  • Safety, tolerability, and biomarkers of the treatment of mice with aerosolized Toll-like receptor ligands
    Frontiers in Pharmacology. 2014 06 February. doi: 10.3389/fphar.2014.00008
  • Pneumonia during remission induction chemotherapy in patients with acute leukemia
    Annals of the American Thoracic Society. 2013 Oct;10(5):432-40. doi: 10.1513
  • Stimulating Natural Defenses
    International Innovation. 2013, September.
  • Lung epithelial cells are essential effectors of inducible resistance to pneumonia
    Mucosal Immunology. 2013, doi: 10.1038/mi.2013.26.
  • Toll-Like Receptor-2/6 and Toll-Like Receptor-9 agonists suppress viral replication but not airway hyperreactivity in guinea pigs
    American Journal of Respiratory Cell and Molecular Biology. 2013, Jun;48(6):790-6.
  • Synergistic TLR2/6 and TLR9 Activation Protects Mice against Lethal Influenza Pneumonia
    PLoS ONE, 2012, 7:e30596
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Pulmotect, Inc.